Scientific Research

Dr Amin Jurdi participated in a study to compare maternal and neonatal outcomes of twin gestations in nulliparous and multiparous women. At the end of the study, Nulliparous women with twin gestations were found to be at a significantly higher risk for preterm delivery and cesarean delivery compared with multiparous women. Although this higher risk was not translated into higher perinatal mortality, the study concluded that these women should always be monitored closely and counseled regarding these risks and their attendant morbidity.

Ovarian reserve testing with serum anti-Müllerian hormone (AMH) can provide information about a woman's fertility potential. During his medical research, Dr Amin Jurdi assessed the interest and knowledge among women of reproductive age about ovarian reserve testing and analyzed the impact of AMH measurements on the success of pregnancy. Dr Jurdi found that most women are interested in ovarian reserve testing to seek reassurance about AMH level and gain insight to their fertility parameters prior to planning future pregnancies. Dr Jurdi also noticed that women with lower than normal AMH levels seek counseling earlier and attempt to achieve pregnancy sooner than other women. such women were also keen to discuss fertility preservation options available compared to women who had normal AMH measurements.

During his practice, Dr Amin Jurdi performed Total Laparoscopic Hysterectomy (TLH) surgery as an alternative to open classical surgery on a large number of women and noted that the laparoscopic approach resulted in less pain and nausea following operation and a decreased hospital stay and recovery time for patients. Dr Jurdi also analyzed risk associated with TLH surgery especailly in women with history of previous open surgery (ex: myomectomy, c-section ) and concluded that TLH in such patients can be performed safely as such history had no effect on the major complication rate.

Endometriosis is characterized by frequent recurrences of symptoms and lesions.Long periods of medical management may be needed until pregnancy desire or physiologic menopause. During his research work, Dr Amin Jurdi found that Estrogen-progestins with the lowest possible estrogen dose should be chosen to combine optimal lesion suppression and thrombotic risk limitation. The research further concluded that progestins should be suggested in women who do not respond or manifest intolerance to estrogen-progestins and in those with dyspareunia and/or deep lesions and high thrombotic risk .Dr Jurdi also noted that Estrogen-progestins and progestins reduce the incidence of postoperative endometrioma recurrence.

Polycystic ovary syndrome (PCOS) is the most common ovarian disorder associated with androgen excess in women that leads to clinical hyperandrogenism and/or anovulation and infertility. Its diagnosis is based on consensual diagnostic criteria, but which are likely to change in the near future with the rise of the interest of new markers such as AMH. The etiology of PCOS is multifactorial and Dr Amin Jurdi utilizes ultrasound, biomarkers and clinical correlation to establish diagnosis. During his research Dr Jurdi noted that PCOS management is optimal when oral combined oral contraceptive treatment is coupled with life style changes such as weight reduction, diabetes control and exercise in addition to anti-androgen use to control for acne and hirsutism.

Perhaps the most important step in a patient's IVF cycle is the egg yield after retrieval but the success rate determining step is no doubt Embryo transfer. During his practice Dr Amin Jurdi conducted a study comparing success rates of Ultrasound-guided Embryo transfer vs Non Ultrasound-guided Embryo transfer and analyzed the impact of technique on pregnancy success rates. In ultrasound guided transfers, embryos were placed in close proximity to the fundal part of uterus as depicted by ultrasound. On the other-hand Uterine Cervical Length (UCL) was measured during Blind embryo transfers and embryos were placed at a distance = UCL-1cm.The results showed no statistically significant difference between the two techniques in term of pregnancy success rates.